We consider a dermal filler as pure if it contains minimal amounts of synthetic additives.

Our gel technology SHAPE™ (Smart Hyaluronic Acid PurE Technology) utilises the natural and entangled form of the hyaluronic acid (HA) molecule. This means that we just have to add minimal amounts of the cross-linking agent BDDE (1,4-butanediol diglycidyl ether) to create durable gels. Only 1% of the HA molecule is modified in the Decoria^® dermal fillers, making Decoria^® the purest HA dermal filler range.

The following indications are recommended for the Decoria^® dermal fillers:

Decoria^® Pure Cheeks: Correction of midface volume deficit and contouring in the cheek region.

Decoria^® Pure Lips: Augmentation and contouring of the lips, including definition of the vermilion border, and correction of perioral rhytids.

Decoria^® Pure Volume: Treatment of medium to deep wrinkles and folds of the face, such as nasolabial folds.

Decoria^® Pure Jawline: Coming soon! Augmentation, contouring, and correction of jawline and chin profile.

The Decoria^® dermal fillers may only be used as an intradermal implant by properly trained, qualified physicians or authorised staff members in accordance with national legislation.

Please read more in the Instructions For Use (IFU) that can be downloaded on the Decoria^® product pages.

Safety data can be found in the Decoria^® Instructions For Use (IFU) where you will find information about warnings and precautions, contraindications and patient information.

The Decoria^® dermal fillers may only be used as an intradermal implant by properly trained, qualified physicians or authorised staff members in accordance with national legislation.

When there is a high degree of modification, the body may perceive the filler gel as a foreign and there is a higher risk of an immunological reaction.*

Highly cross-linked gels may also be more difficult to dissolve with hyaluronidase.*

The degree of modification varies substantially between filler brands, from the very low degree of 1% that characterises all Decoria® fillers to 8% or more.*

*Wu G.T. et al., Hyaluronic Acid Basics and Rheology, Facial Plast Surg Clin North Am. 2022 Aug;30(3):301-308.

The hyaluronic acid (HA) molecules in dermal fillers are cross-linked to increase the durability of the gel. The most common cross-linking agent is 1,4-butanediol diglycidyl ether (BDDE)*, which is also used to produce all Decoria^® fillers.

When a filler gel degrades, BDDE breaks down into harmless byproducts or into byproducts that are identical to substances already found in the skin.*

*De Boulle K et al., A Review of the Metabolism of 1,4-Butanediol Diglycidyl Ether–Crosslinked Hyaluronic Acid Dermal Fillers, Dermatol Surg. 2013 Dec; 39(12): 1758–1766.

All Decoria^® dermal fillers are based on bio-fermented hyaluronic acid (HA) where the natural entangled form of the HA molecular strands is preserved. Thereby, only a minimal number of cross-links is needed to produce durable gels.

When instead ´straight´ HA molecular strands are utilised, more cross-links are needed to make a durable filler gel.

The degree of modification is also dependent on the number of failed links, where there is only a ‘pendant’ on an HA molecule and no effective linking. Pendant modifications do not contribute to filler durability.*

*Wu G.T. et al., Hyaluronic Acid Basics and Rheology, Facial Plast Surg Clin North Am. 2022 Aug;30(3):301-308..